##### Department of Mathematics,

University of California San Diego

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### Informal Seminar on Mathematics and Biochemistry-Biophysics

## Lei Zhang

#### International Center for Math Research and Center for Quantitative Biology, Peking University

## Computation of Rare Events and its Applications in Biology

##### Abstract:

The dynamics of complex biological systems is often driven by multiscale, rare but important events. In this talk, I will introduce the numerical methods for computing transition states, and then give two examples in distinct biological systems: one is a multiscale stochastic model to investigate a novel noise attenuation mechanism that relies on more noises in different cellular processes to coordinate cellular decisions during embryonic development; the other is a phase field model to study the neuroblast delamination in Drosophila.

Hosts: Li-Tien Cheng and Bo Li

### January 21, 2016

### 1:00 PM

### AP&M 5829

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