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Department of Mathematics,
Department of Mathematics,
University of California San Diego
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Informal Seminar on Mathematics and Biochemistry-Biophysics
Wei Wang
UCSD
Computational Determination of Protein-Ligand Binding Specificity
Abstract:
I will discuss the computational methods based on a continuum solvent model to calculate binding affinity for protein-ligand systems. I will also show how such models can be combined with statistical learning methods to predict binding specificity of protein recognition. An application of these methods to understand drug resistance will exemplify its usefulness in drug development.
Hosts: Li-Tien Cheng and Bo Li
January 17, 2013
1:00 PM
AP&M 5829
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